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103 matching jobs for “Senior Principal AI Engineer”

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Exact titles rank first, then title variations and keywords in descriptions. These labels aren't qualification scores. Without keywords, recently added jobs appear first.

Vertex Pharmaceuticals

Senior Principal AI Engineer

Boston, Massachusetts, United States

  • Full time
  • Regular

Pay posted by employer$188,000–$282,000

Vertex is seeking a Senior Principal AI Engineer to design, build, and optimize the shared platform capabilities that power AI-enabled products and …

Added Oct 18, 2026

Vertex Pharmaceuticals

Senior Principal AI Engineer

Boston, Massachusetts, United States

  • Full time
  • Regular

Pay posted by employer$188,000–$282,000

Vertex is seeking a Senior Principal AI Engineer to define and build the foundational enterprise AI platform that powers intelligent applications across the …

Added Oct 18, 2026

Danaher

Principal AI Engineer

Bengaluru, India

  • Regular

… and accelerated intelligence. Learn about the Danaher Business System which makes everything possible. The Principal AI Engineer – R&D is a senior individual-contributor technology leader responsible for defining the …

Added Oct 15, 2026

Johnson & Johnson

Principal AI Engineer

Raritan, New Jersey, United States of America

Pay posted by employer$102,000–$177,100

J&J is currently seeking a Principal AI Engineer for their Technology Services team based in Raritan, NJ. The Principal AI Engineer leads the …

Added Oct 18, 2026

Bristol-Myers Squibb

Principal AI Engineer

Hyderabad - TS - IN

  • Full time
  • Regular

We are seeking an AI Engineer to support the AI Enablement Team in developing and deploying enterprise-grade generative AI …

Added Oct 15, 2026

Northern Trust

Principal, AI Engineer

Chicago, Illinois, United States

  • Full time
  • Regular

Pay posted by employer$137,400–$233,600 USD

Summary As a key member of our AI Engineering team who builds, ships, and owns production-grade generative AI systems, the lead the design …

Added Oct 16, 2026

Broadcom

Principal AI Development Engineer

San Jose, California, United States

  • Full time
  • Regular

Pay posted by employer$118,800–$190,000 per year

Broadcom’s GTO team is seeking a high-energy, visionary Principal AI Development Engineer to serve as a strategic leader and the primary architect of our AI transformation. …

Added Oct 5, 2026

General Motors

Principal Engineer, AI Acceleration

Warren, Michigan, United States +1 location

  • Hybrid
  • Full time
  • Regular

… more time solving the problems that matter most in their domains. The Role At General Motors, we are using AI to simplify how work gets done—reducing manual effort, removing friction, and helping engineers and …

Added Oct 16, 2026

General Motors

Principal AI/ML Engineer

Sunnyvale, California, United States +1 location

  • Hybrid
  • Full time
  • Regular

Pay posted by employer$296,300–$423,900

… smarter, and more connected, shaping the future of transportation on a global scale. We are looking for a Principal Technical Lead Manager (TLM) to lead the Trajectory Generation team within the Embodied AI organization. …

Added Oct 12, 2026

Vertex Pharmaceuticals

Senior Principal AI Platform Engineer, Data & AI Platform

Boston, Massachusetts, United States

  • Full time
  • Regular

Pay posted by employer$188,000–$282,000

… have data “at their fingertips”, with the patterns and technology to support AI adoption at scale. As a Senior Principal AI Engineer in the Data Platforms team, you will unlock and accelerate AI by designing the reusable components, starter …

Added Oct 18, 2026

Abbott Laboratories

Principal AI Platform Engineer

United States - Illinois - Abbott Park

Pay posted by employer$149,300–$298,700

… leadership role accountable for the architecture, engineering, and reliability of Abbott's enterprise AI Platform: the control plane and paved road that let teams build, deploy, and operate enterprise GenAI and …

Added Oct 15, 2026

General Motors

Principal AI / ML Engineer - Embodied AI

Mountain View, California, United States

  • Hybrid
  • Full time
  • Regular

Pay posted by employer$296,300–$453,900

… safer, smarter, and more connected, shaping the future of transportation on a global scale. Role: As a Principal Technical Lead in the Embodied AI organization, you will be a senior individual contributor driving …

Added Oct 12, 2026

Northern Trust

Sr Principal Software Engineer, AI Security Platform

Chicago, Illinois, United States

  • Full time
  • Regular

Pay posted by employer$164,600–$288,000 USD

… sophisticated clients using leading technology and exceptional service. We are seeking a highly experienced Senior Principal Software Engineer to support technical development of our AI-powered Code Security Scanner …

Added Oct 16, 2026

General Motors

Principal Software Engineer - Vehicle AI

Mountain View, California, United States +1 location

  • Hybrid
  • Full time
  • Regular

Pay posted by employer$238,700–$365,700

… Role General Motors is building the future of intelligent in-cabin experiences, and we are looking for a Principal Software Engineer to serve as a technical leader and authority for our next-generation In-Vehicle AI …

Added Oct 12, 2026

Fannie Mae

Principal, AI Solutions

Reston, Virginia, United States +2 locations

  • Flex
  • Full time
  • Regular

THE IMPACT YOU WILL MAKE As Principal, AI Solutions, you will lead a high‑impact, forward‑deployed AI solutions team responsible for turning …

Added Oct 15, 2026

Danaher

Principal Full Stack Engineer (Agentic AI)

Cambridge, United Kingdom

  • Regular

… positive impact on society. Learn about the Danaher Business System which makes everything possible. The Principal Full Stack Engineer (Agentic AI) is responsible for accelerating the development of our Agentic AI platform …

Added Oct 15, 2026

HP

Principal AI Data Scientist

Spring, Texas, United States +1 location

  • Full time
  • Reg Employee

Pay posted by employer$147,050–$230,850 per year

… recommendations to shape the future direction of models and digital solutions. • Manages relationships with senior business partners to evaluate and foster data driven innovation, provides domain-specific expertise in …

Added Oct 12, 2026

Northern Trust

Principal Security Engineer – AI & Copilot Data Protection

Chicago, Illinois, United States

  • Full time
  • Regular

Pay posted by employer$137,400–$233,600 USD

… world’s most sophisticated clients using leading technology and exceptional service. Role Summary Seeking a Principal‑level individual contributor to lead the secure enablement of Microsoft 365 Copilot and enterprise AI …

Added Oct 16, 2026

Location reference: GeoNames (CC BY 4.0), normalized by Referizz.

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